GLP-1 체중 감량 프로그램

What is GLP-1?

Semaglutide is a medication used to treat type 2 diabetes and as a weight loss medication. It belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists.

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How does GLP-1 work in our body?

GLP-1 works by mimicking the effects of a hormone called GLP-1, which is produced in the gut and is involved in regulating appetite and blood sugar levels. By activating the GLP-1 receptors in the brain, semaglutide can reduce feelings of hunger and increase feelings of fullness, leading to a decrease in calorie intake.

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Additionally, GLP-1 may slow down the emptying of the stomach and reduce the absorption of glucose from the intestines, leading to lower blood sugar levels and a decrease in insulin resistance.

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These mechanisms of action can help individuals lose weight and improve their overall health. However, it's important to note that medication alone is not sufficient for long-term weight loss and should be combined with a healthy diet and regular exercise for best results.

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Are there any side effects of using GLP-1?

Common side effects of GLP-1 include nausea, vomiting, diarrhea, constipation, stomach pain, and decreased appetite. However, some individuals may experience more serious side effects such as pancreatitis, kidney problems, or gallbladder problems.

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Our team will closely monitor the patient throughout the treatment period to address any concerns or issues that arise promptly.

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How safe is GLP-1?

GLP-1 went through a rigorous process of clinical trials to gain approval from the US Food and Drug Administration (FDA) for weight loss. Here is an overview of some of the key clinical trials:

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• STEP trials: GLP-1 Treatment Effect in People with Obesity (STEP) trials were a series of four clinical trials that evaluated the safety and efficacy of semaglutide for weight loss. In these trials, more than 4,500 participants with overweight or obesity were enrolled and treated with semaglutide or a placebo for up to 68 weeks. The trials found that semaglutide was associated with significant weight loss compared to placebo, and that it was generally well-tolerated.
   

• SUSTAIN trials: GLP-1 has been used for several years to treat type 2 diabetes under the brand name Ozempic. The GLP-1 Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN) trials evaluated the safety and efficacy of GLP-1 for the treatment of diabetes. These trials also included patients with overweight or obesity and found that GLP-1 was associated with significant weight loss.
   

• PIONEER trial: The Peptide InnOvatioN for Early diabEtes tReatment (PIONEER) trial evaluated the safety and efficacy of GLP-1 for the treatment of type 2 diabetes. The trial included more than 1,800 participants and found that GLP-1 was associated with significant weight loss.
   

 

Overall, these clinical trials suggest that GLP-1 is a safe and effective treatment for weight loss. However, as with any medication, it's important to discuss the potential risks and benefits with your healthcare provider before starting treatment.